How A2X Works

There are 2 major problems with most "anxiety remedies" that are available today.

  1. Many of the herbs in these remedies are often used on their own as sleep aids. They essentially combine several different sleeping remedies into one pill. When many of them are packed together into one capsule, they can often interact with each other and cause severe drowsiness. They try to sell you on the quantity of herbs in their remedy without putting any thought into how that formula will actually affect the people who take it.
  2. Although their drowsy side effects may be unwanted, these remedies might actually prevent you from experiencing the symptoms of your anxiety. However, that is exactly the problem. These remedies simply make you feel "numb" so that you can avoid feeling the effects of stress and anxiety in your body. But they do not actually treat the source of these feelings. Essentially, this makes them into nothing more than herbal tranquilizers.

However, A2X takes a different approach.

Rather than pack as many ingredients as possible into one pill, we designed A2X with the usefulness of the entire formula in mind. We carefully chose every ingredient in A2X with 3 criteria in mind: (1) its effectiveness in relieving anxiety, (2) its history of safety, and (3) its potential to enhance the effectiveness of the other ingredients in the remedy. As a result, it is not the individual effectiveness of each ingredient that makes A2X great. Rather, it is the "teamwork" between the ingredients to form one complete remedy that makes A2X truly powerful.

In addition, A2X is unique in that it has been designed to help you overcome the source of your feelings of anxiety and nervousness, rather than make you "numb" to your symptoms. The natural ingredients in A2X have been scientifically shown to boost the levels of two natural chemicals in your body, GABA and serotonin. These two neurotransmitters play a key role in your body’s anxiety response. Low levels of either GABA or serotonin are linked to heightened levels of nervousness and worry. For this reason, the primary cause of anxiety may be rooted in the body’s deficiency in these two powerful neurotransmitters.

The function of GABA and serotonin in your body can be compared to speed controllers: they regulate the speed of communication between neurons in the brain. When your brain is relaxed and stress-free, these two inhibitory neurotransmitters are found in high quantities. They prevent the synapses in your brain from relaying information to each other too quickly, resulting in a calm and peaceful mood. However, when your brain is stressed, GABA and serotonin levels are low. Without these neurological "speed controllers," your brain becomes overstimulated and communication gets out of control. Worries fill your mind and anxiety paralyzes your body.

It is completely normal to have fluctuating levels of GABA and serotonin depending on your mood and surroundings. They are part of your natural fight-or-flight response, and are critical in making sure your mind is highly alert when you are in danger. However, some people have been shown to have chronically low levels of GABA and serotonin. It is no coincidence that many of these individuals struggle with anxiety and depression.

If you experience anxiety, fatigue, stress, social withdrawal, low-self esteem, or depression, you may be deficient in GABA and serotonin. Chronically low levels of GABA and serotonin can cause constant frenzied communication within your brain. It is for this reason that simple negative thoughts that would not normally cause anxiety might leave you with an overwhelming sense of worry or panic.

The good news is that low levels of GABA and serotonin can be restored. One method is with SSRI prescription medication. SSRI stands for Selective Serotonin Re-Uptake Inhibitors.

These medications partially block the reabsorption of serotonin, which causes more serotonin to be available to control the communication in the brain. By boosting the amount of available serotonin, SSRIs are able to calm an overstimulated brain, and have been shown to effectively treat depression and anxiety disorders.

Unfortunately, SSRIs can cause many unwanted side effects, including:

If you are concerned by the long list of side effects that SSRIs can cause, there are a few natural alternatives that have been shown to boost levels of GABA and serotonin without unwanted side effects. Three of the most powerful alternative remedies that have been scientifically shown to help boost levels of GABA and serotonin are passion flower, ashwagandha root, and l-theanine. It is no coincidence that each of these three natural remedies is a cornerstone in the A2X formula.

Passion flower’s ability to promote a state of calm and relaxation have long been noted. However, it was only in recent years that the mechanisms behind passion flower’s calming effects has been discovered. Passion flower helps relieve feelings of nervousness and worry in two different ways:

  1. New studies have indicated that the amino acids in passion flower, particularly alanine, can raise the levels of GABA in the body.
  2. Studies have shown that chrysin, one of the flavonoids in passion flower, can enhance the activity of GABA that is already produced by the body. Chrysin has been shown to act like a benzodiazepine in the brain and boost the effect GABA at the GABA-A receptors, thus allowing your brain to use your naturally-generated GABA more efficiently.

Several clinical studies have confirmed passion flower’s effectiveness against anxiety and depression. One particular double-blind study suggested that passion flower was as effective in relieving anxiety symptoms as oxazepam, a prescription-level benzodiazepine.

While the mechanism behind its anti-anxiety properties is not yet fully understood, ashwagandha root is thought to activate the brain’s receptors for GABA and serotonin. Behavioral experiments have shown ashwagandha root to behave like a GABA agonist, as shown in its ability to promote the growth of nerves in patients with tardive dyskinesia within 7 days. Medical researchers have suggested that the withanolides and sitoindosides, along with saponins and assorted minerals, in ashwagandha root are responsible for the herb’s anxiolytic effects. These conclusions have been verified by several studies, including one in which treatment with ashwagandha root was shown to improve anxiety reduction by up to 50 percent over treatment with psychotherapy.

While ashwagandha root helps the body make more efficient use of GABA, l-theanine has been shown to boost the body’s production of GABA. This phenomenon is thought to be caused by l-theanine’s ability to block the binding of L-glutamic acid to the glutamate receptors in the brain. Just as the inhibitory neurotransmitters GABA and serotonin act as speed controllers, glutamic acid is an excitatory neurotransmitter that spurs faster communication in the brain. When anxiety strikes, the body releases large quantities of glutamic acid to stimulate the brain into action. But if l-theanine helps block glutamic acid from binding to glutamate receptors, the stimulating effects of this excitatory neurotransmitter can be reduced. This helps keep the brain calm and prevents stresses or worries from spiraling out of control. Furthermore, when l-theanine helps prevent the body from absorbing glutamic acid released under stress, the body recycles the glutamic acid and converts it into GABA. These findings are confirmed by several studies indicating l-theanine’s anxiolytic effects, including one study that showed l-theanine significantly prevented a rise in blood pressure during a stressful mental task.

You may be wondering, "If the goal is to boost levels of GABA, why don’t I just go straight to the source and take GABA supplements?" In theory, that strategy would work perfectly. But in practice, it has little to no effect. Why? The blood-brain barrier.

When healthy, your blood-brain barrier acts like an impenetrable forcefield that prevents any dangerous bacteria or toxins that you might have eaten from affecting vital brain tissues. GABA must act within the nervous system in order to calm the mind. When you consume a GABA supplement, it is absorbed into the bloodstream through your gastrointestinal tract, but it cannot permeate the blood-brain barrier and act within the brain.

As a result, a much more effective way to boost GABA is by indirectly boosting its production and efficiency through the use of natural remedies like passion flower, ashwagandha root, and l-theanine. But each remedy may not be enough on its own to exert the kind of influence required on your brain in order to calm your stress and anxiety.

That is why we combined each of these three remedies into one powerful formula, A2X. Because each of the three primary ingredients in the A2X formula can help relieve anxiousness and worry through multiple different mechanisms, they can act together as a team to tackle anxiety from all angles. And only A2X combines the most efficient quantities of these three natural remedies into one simple, easy-to-take capsule for everyday convenience. Ultimately, all the science and research behind the A2X formula fall to the wayside. The only thing that matters is how it works for you.