I've been using this product on and off for a year now. I mainly use it when I forget to take my medication Venlafaxine (generic Effexor)on time and it's too late to take the dose. If I don't take it, I end up with heavy eyes and a headache the next day. I usually feel mentally unclear, if you will. I can function, just not totally "with it". A2X has been great! Its also time for a new bottle!